Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085926 | 0.81 | SLC6A4 (0.55) | SLC6A4SLC6A3SLC6A2S1PR1 | |
| SCHEMBL9062092 | 0.81 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2S1PR1 | |
| Bromide SCHEMBL11634915 | 0.80 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2ICMT | |
| SCHEMBL3518765 | 0.78 | SLC6A4 (0.69) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9563801 | 0.76 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2S1PR1ICMT | |
| SCHEMBL10590549 | 0.76 | S1PR1 (0.47) | SLC6A4SLC6A3SLC6A2S1PR1 | |
| SCHEMBL2834145 | 0.76 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5140945 | 0.76 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14347887 | 0.76 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2ICMT | |
| SCHEMBL9563865 | 0.76 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2S1PR1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976513-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sepracor, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |