Iodide

Iodide

SCHEMBL5087267

CCCCc1ccc(N)c(CCCC)c1CCCC.I

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.47
TYR P14679 3/20 0.40
TLR8 Q9NR97 2/20 0.38
CTRC Q99895 1/20 0.37
HTT P42858 2/20 0.34
NPC1 O15118 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
NOS2 P35228 2/20 0.34
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX5 P09917 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1239687 0.98 SKP2 (0.48) SKP2TYRTLR8CTRCHTT
Bromide SCHEMBL5091368 0.96 SKP2 (0.47) SKP2TYRTLR8CTRCHTT
Water SCHEMBL187705 0.96 SKP2 (0.47) SKP2TYRTLR8CTRCHTT
Hydrochloric Acid SCHEMBL4364768 0.96 SKP2 (0.47) SKP2TYRTLR8CTRCHTT
Hydrochloric Acid SCHEMBL7642029 0.96 SKP2 (0.47) SKP2TYRTLR8CTRCHTT
Iodide SCHEMBL5087542 0.94 TYR (0.43) SKP2TYRTLR8HTTMEN1
Iodide SCHEMBL5088359 0.92 TYR (0.46) SKP2TYRTLR8HTTHPGD
SCHEMBL29193291 0.92 TYR (0.46) SKP2TYRTLR8HTTMEN1
SCHEMBL2400391 0.92 TYR (0.44) SKP2TYRTLR8HTTMEN1
SCHEMBL1704787 0.90 TYR (0.47) SKP2TYRTLR8HTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113087625-B Method for synthesizing benzyl acetate by utilizing combined catalytic system 潜江新亿宏有机化工有限公司 2022-04-01 CN claimed
CN-113087625-A Method for synthesizing benzyl acetate by utilizing combined catalytic system 潜江新亿宏有机化工有限公司 2021-07-09 CN claimed
CN-113087625-B Method for synthesizing benzyl acetate by utilizing combined catalytic system 潜江新亿宏有机化工有限公司 2022-04-01 CN disclosed
CN-113087625-A Method for synthesizing benzyl acetate by utilizing combined catalytic system 潜江新亿宏有机化工有限公司 2021-07-09 CN disclosed
US-20080214386-A1 Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-09-04 US disclosed