Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.83 |
| ▸ | HTR2A | P28223 | 4/20 | 0.83 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29060377 | 1.00 | HRH1 (0.83) | HRH1HTR2ATAAR1SIGMAR1SLC7A5 | |
| SCHEMBL1204774 | 1.00 | HRH1 (0.83) | HRH1HTR2ATAAR1SIGMAR1SLC7A5 | |
| SCHEMBL11329969 | 1.00 | HRH1 (0.83) | HRH1HTR2ATAAR1SIGMAR1SLC7A5 | |
| SCHEMBL2849801 | 1.00 | HRH1 (0.83) | HRH1HTR2ATAAR1SIGMAR1SLC7A5 | |
| SCHEMBL2836377 | 1.00 | HRH1 (0.83) | HRH1HTR2ATAAR1SIGMAR1SLC7A5 | |
| SCHEMBL11328616 | 1.00 | HRH1 (0.83) | HRH1HTR2ATAAR1SIGMAR1SLC7A5 | |
| Hydrochloric Acid SCHEMBL11757649 | 0.98 | HRH1 (0.79) | HRH1HTR2ATAAR1SIGMAR1SLC7A5 | |
| SCHEMBL4403161 | 0.98 | HRH1 (0.86) | HRH1HTR2ATAAR1SIGMAR1SLC7A5 | |
| SCHEMBL157808 | 0.91 | HRH1 (1.00) | HRH1HTR2ATAAR1SIGMAR1 | |
| Bromide SCHEMBL10687139 | 0.88 | HRH1 (0.95) | HRH1HTR2ATAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| EP-1042291-B1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE CO CHEM PHARM FAB (DE) | 2005-07-13 | — | — | EP | disclosed |
| EP-1042291-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | Klinge Pharma GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031064-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |
| EP-0332247-A1 | Lubricating compositions containing complexes endowed with anti-oxidant activity | AGIP PETROLI S.p.A. (IT) | 1989-09-13 | — | — | EP | disclosed |
| US-4111821-A | A BIS(ALKYL) PHTHALATE, AN ADDITIVE SYSTEM OF ALKYL METHACRYLATE-N-VINYLPYRROLIDONE COPOLYMER, HINDERED PHENOL ANTIOXIDANT | TENNECO CHEMICALS, INC. (US) | 1978-09-05 | — | — | US | disclosed |