Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 15/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7456360 | 0.95 | ADORA2A (0.63) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7222053 | 0.93 | ADORA2A (0.69) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7222050 | 0.93 | ADORA2A (0.69) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5086106 | 0.93 | ADORA2A (0.61) | ADORA2AADORA3ADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL7224383 | 0.92 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL7224380 | 0.92 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7452884 | 0.91 | ADORA2A (0.60) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5093553 | 0.90 | ADORA2A (0.58) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7231840 | 0.90 | ADORA2A (0.58) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7231838 | 0.90 | ADORA2A (0.58) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4156035-B2 | — | — | 2008-09-24 | — | — | JP | claimed |
| EP-0948509-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-16 | — | — | EP | claimed |
| US-6426337-B1 | ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-07-30 | — | — | US | claimed |
| JP-2001506668-A | — | — | 2001-05-22 | — | — | JP | claimed |
| EP-0948509-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-10-13 | — | — | EP | claimed |
| WO-1998028319-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-07-02 | — | — | WO | claimed |