Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5060532 | 0.83 | GRIK1 (0.37) | GRIK1GRIK2CPA1TSHRCA2 | |
| SCHEMBL5377593 | 0.81 | GRIK1 (0.42) | GRIK1GRIK2CPA1TSHRALDH1A1 | |
| SCHEMBL5508483 | 0.80 | GRIK1 (0.38) | GRIK1GRIK2CPA1TSHRALDH1A1 | |
| SCHEMBL1728215 | 0.79 | — | — | |
| SCHEMBL629461 | 0.79 | — | — | |
| SCHEMBL6729775 | 0.79 | — | — | |
| SCHEMBL11869712 | 0.77 | — | — | |
| SCHEMBL28717121 | 0.77 | USP2 (0.33) | TSHRUSP2CA2MAPK1CA1 | |
| Hydrogen Sulfide SCHEMBL27837245 | 0.77 | GRIK1 (0.53) | GRIK1GRIK2CPA1TSHRUSP2 | |
| SCHEMBL6724705 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312112-A1 | Lubricating formulations for dispersancy and temperature, friction, and wear reduction | LYON DEVELOPMENT CORPORATION | 2008-12-18 | — | — | US | disclosed |