⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2109211 | 0.73 | — | — | |
| SCHEMBL10384145 | 0.69 | — | — | |
| SCHEMBL1148828 | 0.67 | — | — | |
| SCHEMBL3380839 | 0.64 | — | — | |
| SCHEMBL17910251 | 0.63 | MEN1 (0.33) | — | |
| SCHEMBL3750985 | 0.63 | — | — | |
| SCHEMBL227419 | 0.63 | — | — | |
| SCHEMBL9894655 | 0.62 | — | — | |
| SCHEMBL11334423 | 0.60 | — | — | |
| SCHEMBL1148848 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432383-B2 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE-SERIPHARM (FR) | 2008-10-07 | — | — | US | claimed |
| US-20070208185-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | CHANTELOUP LUC | 2007-09-06 | — | — | US | claimed |
| US-7220871-B2 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE SERIPHARM (FR) | 2007-05-22 | — | — | US | claimed |
| US-20050222089-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | CHANTELOUP LUC | 2005-10-06 | — | — | US | claimed |
| US-6825365-B2 | FORMED AS ENANTIOMERS OF CIS-BETA-PHENYLGLYCIDIC ACID/BETA-PHENYLISOSERINE REACT WITH NITRILE COMPOUND VIA RITTER REACTION | NOVASEP (FR) | 2004-11-30 | — | — | US | claimed |
| US-20040220256-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | CHANTELOUP LUC (FR) | 2004-11-04 | — | — | US | claimed |
| US-20020068833-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE SERIPHARM | 2002-06-06 | — | — | US | claimed |
| EP-0863887-B1 | INTERMEDIARY COMPOUNDS FOR THE HEMISYNTHESIS OF TAXANES AND PREPARATION PROCESSES THEREFOR | SERIPHARM (FR) | 2002-01-23 | — | — | EP | claimed |
| EP-0863887-A1 | INTERMEDIARY COMPOUNDS FOR THE HEMISYNTHESIS OF TAXANES AND PREPARATION PROCESSES THEREFOR | Societé d'Etude et de Recherche en Ingenierie Pharmaceutique Seripharm (FR) | 1998-09-16 | — | — | EP | claimed |
| WO-1997015562-A1 | INTERMEDIARY COMPOUNDS FOR THE HEMISYNTHESIS OF TAXANES AND PREPARATION PROCESSES THEREFOR | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE SERIPHARM (FR) | 1997-05-01 | — | — | WO | claimed |
| US-7432383-B2 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE-SERIPHARM (FR) | 2008-10-07 | — | — | US | disclosed |
| US-7279586-B2 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE SERIPHARM (FR) | 2007-10-09 | — | — | US | disclosed |
| US-20070208185-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | CHANTELOUP LUC | 2007-09-06 | — | — | US | disclosed |
| US-7220871-B2 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE SERIPHARM (FR) | 2007-05-22 | — | — | US | disclosed |
| US-20050222089-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | CHANTELOUP LUC | 2005-10-06 | — | — | US | disclosed |
| US-6825365-B2 | FORMED AS ENANTIOMERS OF CIS-BETA-PHENYLGLYCIDIC ACID/BETA-PHENYLISOSERINE REACT WITH NITRILE COMPOUND VIA RITTER REACTION | NOVASEP (FR) | 2004-11-30 | — | — | US | disclosed |
| US-20040220256-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | CHANTELOUP LUC (FR) | 2004-11-04 | — | — | US | disclosed |
| US-20020068833-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE SERIPHARM | 2002-06-06 | — | — | US | disclosed |
| EP-0863887-B1 | INTERMEDIARY COMPOUNDS FOR THE HEMISYNTHESIS OF TAXANES AND PREPARATION PROCESSES THEREFOR | SERIPHARM (FR) | 2002-01-23 | — | — | EP | disclosed |
| US-6265587-B1 | REACTING ARYLGLYCIDATE WITH A NITRILE TO OBTAIN B-ARYLISOSERINE DERIVATIVE AND TREATING PRODUCT WITH LEWIS ACID TO OBTAIN OXAZOLINE COMPOUND | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE SERIPHARM (FR) | 2001-07-24 | — | — | US | disclosed |