Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181300 | 1.00 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL16213934 | 1.00 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL4194655 | 1.00 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL13698167 | 1.00 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL16214795 | 1.00 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL4185801 | 1.00 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL31284725 | 1.00 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL4187651 | 0.98 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL4191444 | 0.98 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL4188232 | 0.98 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915146-A2 | NOVEL 1-ARYL-3-AZABICYCLOÝ3.1.0¨HEXANES: PREPARATION AND USE TO TREAT NEUROPSYCHIATRIC DISORDERS | DOV Pharmaceutical, Inc. (US) | 2008-04-30 | — | — | EP | claimed |
| WO-2007016155-A2 | NOVEL 1-ARYL-3-AZABICYCLO[3.1.0]HEXANES: PREPARATION AND USE TO TREAT NEUROPSYCHIATRIC DISORDERS | DOV PHARMACEUTICAL, INC. (US) | 2007-02-08 | — | — | WO | claimed |