Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | SHBG | P04278 | 3/20 | 0.68 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.63 |
| ▸ | G6PD | P11413 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4438224 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 | |
| SCHEMBL1419114 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 | |
| SCHEMBL1418725 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 | |
| SCHEMBL6882171 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 | |
| SCHEMBL6442060 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 | |
| SCHEMBL4944130 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 | |
| SCHEMBL510459 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 | |
| SCHEMBL510947 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 | |
| SCHEMBL6441377 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 | |
| SCHEMBL1419020 | 1.00 | GPBAR1 (0.68) | GPBAR1LMNACYP3A4SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354396-B2 | Identifying compounds that can treat autoimmune conditions; ulcerative colitis, inflammatory bowel disease, Crohn's disease, psoriasis, actinic keratosis, arthritis, multiple sclerosis, optic neuritis | Harbor Therapeutics, Inc. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20080153797-A1 | Drug Identification and Treatment Method | BIOVIE INC. | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153797-A1 | Drug Identification and Treatment Method | PTGER4, PTGER1, IL17A | GPBAR1 349/4885LMNA 4082/4885CYP3A4 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.