⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497180 | 1.00 | — | — | |
| SCHEMBL12327087 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL18954319 | 0.97 | — | — | |
| SCHEMBL21676970 | 0.75 | — | — | |
| SCHEMBL6120496 | 0.73 | — | — | |
| SCHEMBL23737642 | 0.73 | — | — | |
| SCHEMBL12555028 | 0.73 | — | — | |
| SCHEMBL9188946 | 0.72 | HTR2A (0.48) | — | |
| SCHEMBL16240 | 0.72 | — | — | |
| SCHEMBL159060 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216417-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2020-07-09 | — | — | US | disclosed |
| EP-2348125-B1 | Method for the synthesis of a bifunctional complex | NUEVOLUTION AS (DK) | 2017-06-21 | — | — | EP | disclosed |
| US-8206901-B2 | Method for the synthesis of a bifunctional complex | NUEVOLUTION A/S (DK) | 2012-06-26 | — | — | US | disclosed |
| US-8206901-B2 | Method for the synthesis of a bifunctional complex | NUEVOLUTION A/S (DK) | 2012-06-26 | — | — | US | disclosed |
| EP-2348124-A2 | Synthesis of a bifunctional complex | Nuevolution A/S (DK) | 2011-07-27 | — | — | EP | disclosed |
| EP-2348125-A2 | Method for the synthesis of a bifunctional complex | Nuevolution A/S (DK) | 2011-07-27 | — | — | EP | disclosed |
| EP-1558744-B1 | ENZYMATIC ENCODING | NUEVOLUTION AS (DK) | 2011-06-15 | — | — | EP | disclosed |
| US-7405201-B2 | Antibacterial macrocycles | BAYER HEALTHCARE AG (DE) | 2008-07-29 | — | — | US | disclosed |
| EP-1430075-B1 | ANTIBACTERIAL MACROCYCLES | BAYER HEALTHCARE AG (DE) | 2007-01-03 | — | — | EP | disclosed |
| US-20050107288-A1 | Antibacterial macrocycles | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | US | disclosed |
| EP-1430075-A2 | ANTIBACTERIAL MACROCYCLES | Bayer HealthCare AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003024996-A2 | ANTIBACTERIAL MACROCYCLES | BAYER HEALTHCARE AG (DE) | 2003-03-27 | — | — | WO | disclosed |