Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979906 | 0.81 | PPARD (0.42) | TSHRTP53TDP1PPARD | |
| SCHEMBL15241266 | 0.79 | TSHR (0.50) | TSHRTP53TDP1PPARDMAPT | |
| SCHEMBL3985445 | 0.75 | TSHR (0.46) | TSHRTP53TDP1PPARDMAPT | |
| SCHEMBL11433626 | 0.75 | TSHR (0.46) | TSHRTP53TDP1PPARDMAPT | |
| SCHEMBL2990037 | 0.73 | — | — | |
| SCHEMBL9633264 | 0.73 | TSHR (0.55) | TSHRTP53TDP1PPARDMAPT | |
| SCHEMBL28128353 | 0.72 | — | — | |
| SCHEMBL15381120 | 0.72 | — | — | |
| SCHEMBL1292884 | 0.72 | — | — | |
| SCHEMBL14233604 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410935-B2 | Gear fluids | AFTON CHEMICAL CORPORATION (US) | 2008-08-12 | — | — | US | disclosed |
| CN-101096610-A | A gear additive composition | AFTON CHEMICAL CORP (US) | 2008-01-02 | — | — | CN | disclosed |
| US-20070225182-A1 | Gear fluids | AFTON CHEMICAL CORPORATION | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225182-A1 | Gear fluids | PHOSPHO1, F12, PIK3CA | TSHR 2476/4885TP53 3495/4885TDP1 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.