Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 20/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2079857 | 0.99 | CHEK1 (0.57) | CHEK1CCNE1CDK2 | |
| SCHEMBL2076847 | 0.93 | CHEK1 (0.56) | CHEK1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL2076753 | 0.93 | CHEK1 (0.56) | CHEK1CCNE1CDK2 | |
| SCHEMBL5024290 | 0.93 | CHEK1 (0.56) | CHEK1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL2078949 | 0.92 | CHEK1 (0.55) | CHEK1CCNE1CDK2 | |
| SCHEMBL2079314 | 0.90 | CHEK1 (0.59) | CHEK1CCNE1CDK2 | |
| SCHEMBL2077144 | 0.90 | CHEK1 (0.59) | CHEK1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL2080463 | 0.89 | CHEK1 (0.55) | CHEK1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL2078697 | 0.89 | CHEK1 (0.59) | CHEK1CCNE1CDK2 | |
| SCHEMBL5028581 | 0.83 | CHEK1 (0.57) | CHEK1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009005-A1 | AZOLECARBOXAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |