Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 11/20 | 0.38 |
| ▸ | MMP1 | P03956 | 6/20 | 0.38 |
| ▸ | MMP3 | P08254 | 6/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5092125 | 1.00 | CSNK1E (0.51) | CSNK1EKCNH2MMP2MMP1MMP3 | |
| Iodide SCHEMBL5088360 | 1.00 | CSNK1E (0.51) | CSNK1EKCNH2MMP2MMP1MMP3 | |
| Iodide SCHEMBL5084811 | 1.00 | CSNK1E (0.51) | CSNK1EKCNH2MMP2MMP1MMP3 | |
| Iodide SCHEMBL5088224 | 1.00 | CSNK1E (0.51) | CSNK1EKCNH2MMP2MMP1MMP3 | |
| Iodide SCHEMBL5087235 | 1.00 | CSNK1E (0.51) | CSNK1EKCNH2MMP2MMP1MMP3 | |
| Iodide SCHEMBL5088212 | 0.98 | CSNK1E (0.49) | CSNK1EKCNH2MMP2MMP1MMP3 | |
| Bromide SCHEMBL5084978 | 0.97 | CSNK1E (0.51) | CSNK1EKCNH2MMP2MMP1MMP3 | |
| Bromide SCHEMBL5092245 | 0.97 | CSNK1E (0.51) | CSNK1EKCNH2MMP2MMP1MMP3 | |
| Hydrochloric Acid SCHEMBL5092844 | 0.97 | CSNK1E (0.51) | CSNK1EKCNH2MMP2MMP1MMP3 | |
| Bromide SCHEMBL5086754 | 0.97 | CSNK1E (0.51) | CSNK1EKCNH2MMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |