SCHEMBL509211

SCHEMBL509211

OCc1cccc(Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30903815 1.00
SCHEMBL30903816 1.00
SCHEMBL30578990 0.82 KCNH2 (0.39)
SCHEMBL1400836 0.82 KCNH2 (0.39)
SCHEMBL486201 0.82 CCR1 (0.55)
SCHEMBL14835224 0.79 KCNH2 (0.43)
SCHEMBL29712341 0.78
SCHEMBL378811 0.78
SCHEMBL7430287 0.76 ESR1 (0.41)
SCHEMBL10577578 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113979955-B Preparation method of heterocyclic ester compound 河南农业大学 2024-05-14 CN claimed
CN-113979955-A Preparation method of heterocyclic ester compound 河南农业大学 2022-01-28 CN claimed
EP-1304325-A1 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-04-23 EP claimed
EP-0301403-B1 CURING AGENT FOR SYNTHETIC RESINS, COMPOSITIONS CONTAINING THE SAME AND USES OF THEM HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-15 EP claimed
US-4847346-A HYDROXYALKYLPYRIDINE BLOCKED DIISOCYANATES AS CURING AGENTS HOECHST AG (DE) 1989-07-11 US claimed
EP-0301403-A2 Curing agent for synthetic resins, compositions containing the same and uses of them HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-01 EP claimed
US-12534458-B2 Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors MERCK SHARP & DOHME LLC (US) 2026-01-27 US disclosed
WO-2025137541-A1 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2025-06-26 WO disclosed
WO-2025101652-A1 SELECTIVE MAMMALIAN STERILE 20-LIKE KINASE 1 (MST1) MODULATOR COMPOUNDS AS THERAPEUTICS FOR DIABETES AND LIVER REGENERATION THE SCRIPPS RESEARCH INSTITUTE (US) 2025-05-15 WO disclosed
US-20250144093-A1 PYRUVATE KINASE ACTIVATORS FOR USE IN TREATING BLOOD DISORDERS AGIOS PHARMACEUTICALS, INC. 2025-05-08 US disclosed
US-20250101012-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) 2025-03-27 US disclosed
US-12139479-B2 Heterocycle substituted pyridine derivative antifungal agents BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) 2024-11-12 US disclosed
US-20240368147-A1 CYCLIN K DEGRADER ADLAI NORTYE BIOPHARMA CO., LTD. (CN) 2024-11-07 US disclosed
EP-0313630-A1 SUBSTITUTED 2-ACYLPYRIDIN-ALPHA-(N)-HETARYLHYDRAZONES AND MEDICAMENTS CONTAINING SAME. DEUTSCHES AUSSATZIGEN HILFSWER (DE) 1989-05-03 EP disclosed
US-4826833-A ANTIBIOTICS PFIZER INC. (US) 1989-05-02 US disclosed
EP-0301403-A2 Curing agent for synthetic resins, compositions containing the same and uses of them HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-01 EP disclosed
US-4749574-A MICROCAPSULE OF 2-NITROXYMETHYL-6-CHLOROPYRINE OR ITS OCCLUSION COMPOUND WITH B-CYCLODEXTRIN FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-07 US disclosed
EP-0241806-A1 Sustained-release transdermal delivery preparations FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-10-21 EP disclosed
EP-0193164-A2 Sustained-release pharmaceutical preparation which comprised 2-nitroxy-methyl-6-chloropyridine, process for its preparation and use thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-09-03 EP disclosed
EP-0150984-A2 6-(Substituted) methylenepenicillanic and 6-(substituted) hydroxymethylpenicillanic acids and derivatives thereof PFIZER INC. (US) 1985-08-07 EP disclosed