Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | PPARA | Q07869 | 9/20 | 0.46 |
| ▸ | PPARD | Q03181 | 9/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097748 | 0.92 | PPARG (0.45) | PPARGPPARAPPARDFFAR4FFAR1 | |
| SCHEMBL5090441 | 0.91 | PPARD (0.47) | PPARGPPARAPPARDFFAR4FFAR1 | |
| SCHEMBL5102374 | 0.91 | PPARD (0.57) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL5102589 | 0.88 | PPARG (0.50) | PPARGPPARAPPARDP2RX3FFAR1 | |
| SCHEMBL5096638 | 0.84 | PPARD (0.48) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL5096381 | 0.83 | PPARG (0.54) | PPARGPPARAPPARDFFAR4FFAR1 | |
| SCHEMBL5096477 | 0.82 | PPARG (0.47) | PPARGPPARAPPARDP2RX3FFAR1 | |
| SCHEMBL14138236 | 0.81 | PPARD (0.46) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL5102412 | 0.79 | PPARG (0.67) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL5090306 | 0.78 | PPARG (0.50) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207685-A1 | Heterocyclic Compounds As Modulators Of Peroxisome Proliferator Activated Receptors, Useful For The Treatment And/Or Prevention Of Disorders Modulated By A Ppar | ELI LILLY AND COMPANY (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207685-A1 | Heterocyclic Compounds As Modulators Of Peroxisome Proliferator Activated Receptors, Useful For The Treatment And/Or Prevention Of Disorders Modulated By A Ppar | PPARG, PPARD, PPARA | PPARG 1/4885PPARA 3/4885PPARD 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.