SCHEMBL5097457

SCHEMBL5097457

Brc1c(CCCCCCCCCCCOC2CCCCO2)sc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KCNA5 P22460 1/20 0.31
SCN5A Q14524 1/20 0.31
NPY1R P25929 3/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ICAM1 P05362 1/20 0.31
SELE P16581 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8500626 0.74 MEN1 (0.55) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL14469419 0.74 MEN1 (0.55) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL9673310 0.74 KDM4C (0.53) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL80945 0.74 KDM4C (0.46) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL80944 0.73 KDM4C (0.54) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL30516899 0.72 KDM4C (0.47) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL30516905 0.72 KDM4C (0.47) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL30516906 0.72 KDM4C (0.47) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL9574209 0.72 MEN1 (0.53) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL12523969 0.72 MEN1 (0.47) KDM4CMEN1KMT2AL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7416682-B2 Photochromic liquid crystals CHI MEI OPTOELECTRONICS CORPORATION (TW) 2008-08-26 US disclosed
EP-1517977-B1 PHOTOCHROMIC LIQUID CRYSTALS QINETIQ LTD (GB) 2006-10-11 EP disclosed
US-20050258396-A1 Potochromic liquid crystals QINETIQ LIMITED (GB) 2005-11-24 US disclosed
EP-1517977-A1 PHOTOCHROMIC LIQUID CRYSTALS Qinetiq Limited (GB) 2005-03-30 EP disclosed
WO-2004003107-A1 POTOCHROMIC LIQUID CRYSTALS QINETIQ LIMITED (GB) 2004-01-08 WO disclosed