Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168928 | 0.84 | CA12 (0.34) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL28089599 | 0.81 | CA12 (0.31) | CA12CA1CA9 | |
| SCHEMBL7742052 | 0.79 | CA1 (0.36) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL28983307 | 0.79 | EPHX1 (0.33) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL27345447 | 0.77 | — | — | |
| SCHEMBL27998244 | 0.76 | — | — | |
| SCHEMBL28104178 | 0.74 | — | — | |
| SCHEMBL28041462 | 0.74 | — | — | |
| SCHEMBL29876681 | 0.73 | EPHX2 (0.34) | — | |
| SCHEMBL29353408 | 0.73 | EPHX2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130243888-A1 | Composition and Method for the Topical Treatment of Dermatitis | FORD SARA BETH (US) | 2013-09-19 | — | — | US | disclosed |
| WO-2012015789-A2 | COMPOSITION AND METHOD FOR THE TOPICALTREATMENT OF DERMATITIS | FORD SARA BETH (US) | 2012-02-02 | — | — | WO | disclosed |
| US-20120027876-A1 | Composition and Method for the Topical Treatment of Dermatitis | FORD SARA BETH (US) | 2012-02-02 | — | — | US | disclosed |