⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099646 | 1.00 | — | — | |
| SCHEMBL655123 | 0.58 | — | — | |
| SCHEMBL4028990 | 0.58 | — | — | |
| SCHEMBL11378612 | 0.58 | — | — | |
| SCHEMBL10918566 | 0.58 | — | — | |
| SCHEMBL1032876 | 0.58 | — | — | |
| SCHEMBL25078 | 0.58 | — | — | |
| SCHEMBL425203 | 0.58 | — | — | |
| SCHEMBL9145705 | 0.56 | — | — | |
| SCHEMBL3538841 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342026-B2 | Substituted quinolines for the treatment of protozoa and retrovirus co-infections | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2008-03-11 | — | — | US | claimed |
| EP-1351940-B1 | SUBSTITUTED QUINOLINES FOR THE TREATMENT OF PROTOZOAN AND RETROVIRUS CO-INFECTIONS | INST RECH DEVELOPPEMENT IRD (FR) | 2007-07-25 | — | — | EP | claimed |
| US-20050165052-A1 | Substituted quinolines for the treatment of protozoa and retrovirus co-infections | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2005-07-28 | — | — | US | claimed |
| US-7342026-B2 | Substituted quinolines for the treatment of protozoa and retrovirus co-infections | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2008-03-11 | — | — | US | disclosed |
| US-20050165052-A1 | Substituted quinolines for the treatment of protozoa and retrovirus co-infections | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2005-07-28 | — | — | US | disclosed |