⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979174 | 1.00 | — | — | |
| SCHEMBL10980571 | 0.92 | — | — | |
| SCHEMBL14809823 | 0.89 | — | — | |
| SCHEMBL9951637 | 0.84 | — | — | |
| SCHEMBL6364804 | 0.77 | — | — | |
| SCHEMBL112025 | 0.76 | — | — | |
| SCHEMBL4804534 | 0.76 | — | — | |
| SCHEMBL225831 | 0.74 | — | — | |
| SCHEMBL149605 | 0.69 | — | — | |
| SCHEMBL623024 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618101-B1 | BENZOCHROMENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | claimed |
| US-7326447-B2 | Benzochromene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-02-05 | — | — | US | claimed |
| US-20060177603-A1 | Benzochromene derivatives | MERCK PATENT GMBH (DE) | 2006-08-10 | — | — | US | claimed |
| US-7326447-B2 | Benzochromene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-02-05 | — | — | US | disclosed |
| US-20060177603-A1 | Benzochromene derivatives | MERCK PATENT GMBH (DE) | 2006-08-10 | — | — | US | disclosed |