SCHEMBL510185

SCHEMBL510185

COc1cc(-c2cc(OC)c(O)c(-c3ccccc3)c2)cc(-c2ccccc2)c1O

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.54
PDE4B Q07343 2/20 0.53
HK2 P52789 1/20 0.50
SMPD3 Q9NY59 3/20 0.49
PDE4A P27815 1/20 0.49
PDE4C Q08493 1/20 0.49
PDE4D Q08499 1/20 0.49
PTPN1 P18031 1/20 0.49
NOX1 Q9Y5S8 1/20 0.48
ERN1 O75460 2/20 0.47
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
FYN P06241 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aucuparin SCHEMBL11223391 0.86 SMPD3 (0.57) SMPD3NOX1ERN1GAA
SCHEMBL30937381 0.82 ABCC1 (0.55) SMPD3NOX1ERN1
SCHEMBL28633755 0.82 ABCC1 (0.55) SMPD3NOX1ERN1
SCHEMBL5605400 0.80 BACE1 (0.46) BACE1PDE4BHK2PDE4APDE4C
SCHEMBL2649406 0.80 ERN1 (0.51) BACE1PDE4BHK2ERN1
SCHEMBL10130967 0.79 ERN1 (0.48) SMPD3NOX1ERN1GAA
SCHEMBL9469340 0.79 PTPN1 (0.63) BACE1PDE4BPTPN1
SCHEMBL7725113 0.78 KDM4E (0.57) BACE1PDE4BHK2PDE4APDE4C
SCHEMBL29941297 0.78 KDM4E (0.57) BACE1PDE4BHK2PDE4APDE4C
SCHEMBL9812706 0.78 BACE1 (0.51) BACE1PDE4BHK2PDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9096566-B2 Ester group-containing tetracarboxylic acid dianhydride, polyester polyimide precursor, polyesterimide, and methods for producing same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2015-08-04 US disclosed
US-20120029164-A1 ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029164-A1 ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME ALK, ALKBH3, IGLV6-57 BACE1 4178/4885PDE4B 3432/4885HK2 4582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.