SCHEMBL5102256

SCHEMBL5102256

[c]1ccc2c(c1)=C[N]C=2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451931 0.65
SCHEMBL5592509 0.65
SCHEMBL6289934 0.65
SCHEMBL129202 0.59
SCHEMBL15062522 0.57
SCHEMBL15062680 0.57
SCHEMBL71297 0.57
SCHEMBL452033 0.57
SCHEMBL1461411 0.56 KDM4E (0.33)
SCHEMBL62327 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10472381-B2 Sialic acid derivatives REINHARD BROSSMER (DE) 2019-11-12 US disclosed
WO-2018172129-A1 SIALIC ACID DERIVATIVES WITH C-C TRIPLE BOND, AND PREPARATION THEREOF PRESCHER HORST (CH) 2018-09-27 WO disclosed
EP-3129390-A1 SIALIC ACID DERIVATIVES Brossmer, Reinhard (DE) 2017-02-15 EP disclosed
US-20160362436-A1 SIALIC ACID DERIVATIVES BROSSMER REINHARD (DE) 2016-12-15 US disclosed
EP-2797946-B1 SIALIC ACID DIMERS BROSSMER REINHARD (DE) 2016-05-04 EP disclosed
US-9260467-B2 Sialic acid dimers BROSSMER REINHARD (DE) 2016-02-16 US disclosed
WO-2015128344-A1 SIALIC ACID DERIVATIVES BROSSMER REINHARD (DE) 2015-09-03 WO disclosed
EP-2910561-A1 Sialic acid derivatives Brossmer, Reinhard (DE) 2015-08-26 EP disclosed
US-20150005245-A1 Sialic Acid Dimers BROSSMER REINHARD (DE) 2015-01-01 US disclosed
EP-2797946-A1 SIALIC ACID DIMERS Brossmer, Reinhard (DE) 2014-11-05 EP disclosed
WO-2005016926-A1 PYRIDO [3,4-D] PYRIMIDINE DERIVATIVES AS MATRIX METALLOPROTEINASE-13 INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2005-02-24 WO disclosed
US-20040176566-A1 Polymer,method of its preparation, and electronic device MERCK PATENT GMBH (DE) 2004-09-09 US disclosed
EP-1397411-A1 POLYMER, METHOD OF ITS PREPARATION, AND ELECTRONIC DEVICE Koninklijke Philips Electronics N.V. (NL) 2004-03-17 EP disclosed
EP-1290059-A1 METHOD OF PREPARING A POLYMER, METHOD OF PREPARING A COMPOUND, COMPOUNDS, POLYMERS, AND METHOD OF MANUFACTURING AN ELECTRONIC DEVICE Koninklijke Philips Electronics N.V. (NL) 2003-03-12 EP disclosed
US-20030027963-A1 Method of preparing a polymer, method of preparing a compound, compounds, polymers, and method of manufacturing an electronic device KONINLIJKE PHILIPS ELECTRONICS N.V. (NL) 2003-02-06 US disclosed
WO-2002096970-A1 POLYMER, METHOD OF ITS PREPARATION, AND ELECTRONIC DEVICE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2002-12-05 WO disclosed
WO-2001092369-A1 METHOD OF PREPARING A POLYMER, METHOD OF PREPARING A COMPOUND, COMPOUNDS, POLYMERS, AND METHOD OF MANUFACTURING AN ELECTRONIC DEVICE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2001-12-06 WO disclosed
EP-0705857-B1 A process for producing polymers of alpha,omega-unsaturated conjugated compounds AVENTIS RES & TECH GMBH & CO (DE) 2000-01-19 EP disclosed
US-5763539-A Process for producing polymers of α,ω-unsaturated conjugated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-09 US disclosed
EP-0705857-A2 A process for producing polymers of alpha,omega-unsaturated conjugated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-10 EP disclosed