Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17226329 | 0.79 | KMT2A (0.37) | KMT2AALDH1A1MEN1TSHRCYP1A2 | |
| SCHEMBL11941451 | 0.79 | MEN1 (0.33) | KMT2AALDH1A1MEN1TSHRCYP1A2 | |
| SCHEMBL4646027 | 0.78 | MEN1 (0.37) | KMT2AMEN1HCRTR2MAPK1CA1 | |
| SCHEMBL21222679 | 0.78 | KMT2A (0.36) | KMT2AALDH1A1MEN1TSHRCYP1A2 | |
| SCHEMBL583634 | 0.78 | KMT2A (0.38) | KMT2AALDH1A1MEN1TSHRCYP1A2 | |
| SCHEMBL8200484 | 0.77 | KMT2A (0.39) | KMT2AALDH1A1MEN1TSHRCYP1A2 | |
| SCHEMBL5427004 | 0.77 | KMT2A (0.39) | KMT2AALDH1A1MEN1TSHRCYP1A2 | |
| SCHEMBL1967793 | 0.76 | MEN1 (0.35) | KMT2AALDH1A1MEN1TSHRCYP1A2 | |
| SCHEMBL21222559 | 0.76 | KMT2A (0.39) | KMT2AALDH1A1MEN1TSHRCYP1A2 | |
| SCHEMBL1351011 | 0.75 | LATS1 (0.37) | KMT2AALDH1A1MEN1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348344-B2 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | LES LABORATOIRES SERVIER (FR) | 2008-03-25 | — | — | US | disclosed |
| US-20070027191-A1 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | LES LABORATOIRES SERVIER (FR) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027191-A1 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | CHRM1, CHRNA1, CHRNA9 | KMT2A 2244/4885ALDH1A1 680/4885MEN1 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.