Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690348 | 0.91 | MEN1 (0.47) | ALDH1A1KMT2ATHRBKDM4EHTT | |
| SCHEMBL4690971 | 0.82 | KMT2A (0.36) | ALDH1A1KMT2AKDM4EHTTMEN1 | |
| SCHEMBL1843269 | 0.81 | SMYD2 (0.36) | HTTSMN1; SMN2CYP3A4SMYD2 | |
| SCHEMBL4691044 | 0.79 | SMYD2 (0.32) | HTTMAPTSMN1; SMN2CYP3A4SMYD2 | |
| SCHEMBL4687852 | 0.79 | SMYD2 (0.31) | HTTSMN1; SMN2CYP3A4SMYD2 | |
| SCHEMBL4692907 | 0.79 | SMYD2 (0.36) | HTTSMN1; SMN2CYP3A4SMYD2 | |
| SCHEMBL4687409 | 0.79 | SMYD2 (0.36) | KMT2AHTTMEN1GAASMN1; SMN2 | |
| SCHEMBL1844316 | 0.78 | SMYD2 (0.38) | HTTSMN1; SMN2CYP3A4SMYD2 | |
| SCHEMBL4690379 | 0.78 | ABL1 (0.42) | ALDH1A1KMT2AKDM4EHTTMAPT | |
| SCHEMBL4687841 | 0.77 | KMT2A (0.37) | ALDH1A1KMT2AHTTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375115-B2 | 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2008-05-20 | — | — | US | disclosed |