Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 17/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 15/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558484 | 0.85 | S1PR1 (0.60) | S1PR5S1PR1S1PR4S1PR3GRK5 | |
| SCHEMBL3558814 | 0.82 | S1PR1 (0.60) | S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL3552864 | 0.82 | S1PR5 (0.63) | S1PR5S1PR1S1PR4S1PR3GRK5 | |
| SCHEMBL3552008 | 0.81 | S1PR5 (0.51) | S1PR5S1PR1S1PR4S1PR3GRK5 | |
| SCHEMBL3556762 | 0.79 | S1PR1 (0.56) | S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL14423042 | 0.79 | S1PR5 (0.54) | S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL14423049 | 0.78 | S1PR5 (0.56) | S1PR5S1PR1S1PR4S1PR3GRK5 | |
| SCHEMBL3557638 | 0.77 | S1PR1 (0.70) | S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL14423051 | 0.76 | S1PR5 (0.61) | S1PR5S1PR1S1PR3 | |
| SCHEMBL3558716 | 0.76 | S1PR5 (0.51) | S1PR5S1PR1S1PR4S1PR3GRK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015177-A1 | S1P receptor modulating compounds and use thereof | AMGEN INC. | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015177-A1 | S1P receptor modulating compounds and use thereof | S1PR1, S1PR2, S1PR5 | S1PR5 3/4885S1PR1 1/4885S1PR4 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.