Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | TPH1 | P17752 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5116303 | 0.88 | PTPN1 (0.63) | PTPN1SLC7A5ALPIPKMPTGS1 | |
| Phenylalanine SCHEMBL27785427 | 0.83 | SLC7A5 (0.71) | PTPN1PPARGPPARASLC7A11SLC7A5 | |
| SCHEMBL29401985 | 0.83 | SLC7A5 (0.65) | PTPN1SLC7A11SLC7A5ALPIPKM | |
| SCHEMBL29375097 | 0.83 | SLC7A5 (0.65) | PTPN1SLC7A11SLC7A5ALPIPKM | |
| SCHEMBL210104 | 0.83 | SLC7A5 (0.65) | PTPN1SLC7A11SLC7A5ALPIPKM | |
| SCHEMBL93304 | 0.83 | SLC7A5 (0.65) | PTPN1SLC7A11SLC7A5ALPIPKM | |
| SCHEMBL837890 | 0.83 | SLC7A5 (0.65) | PTPN1SLC7A11SLC7A5ALPIPKM | |
| SCHEMBL93303 | 0.83 | SLC7A5 (0.65) | PTPN1SLC7A11SLC7A5ALPIPKM | |
| SCHEMBL29584308 | 0.83 | SLC7A5 (0.65) | PTPN1SLC7A11SLC7A5ALPIPKM | |
| SCHEMBL29554654 | 0.83 | SLC7A5 (0.65) | PTPN1SLC7A11SLC7A5ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481965-B1 | AROMATIC AMINO ACID DERIVATIVES AND MEDICINAL COMPOSITIONS | ENDO HITOSHI (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-7345068-B2 | Aromatic amino acid derivatives and medicinal compositions | Endou, Hitoshi (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20050119256-A1 | Aromatic amino acid derivates and medicinal compositions | HITOSHI ENDOU (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-1481965-A1 | AROMATIC AMINO ACID DERIVATIVES AND MEDICINAL COMPOSITIONS | Endo, Hitoshi (JP) | 2004-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119256-A1 | Aromatic amino acid derivates and medicinal compositions | SLC7A1, SLC1A5, SLC7A5 | PTPN1 1039/4885PPARG 543/4885PPARD 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.