Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 6/20 | 1.00 |
| ▸ | HTR2A | P28223 | 5/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747652 | 0.83 | CHRM1 (0.71) | MCHR1CHRM1HTR2ACNR1RAB9A | |
| SCHEMBL23747448 | 0.82 | CHRM1 (0.69) | MCHR1CHRM1HTR2ARAB9APOLB | |
| SCHEMBL23747369 | 0.81 | CHRM1 (0.69) | MCHR1CHRM1HTR2ACNR1RAB9A | |
| SCHEMBL3879688 | 0.81 | MCHR1 (0.68) | MCHR1CHRM1HTR2ARAB9ANPC1 | |
| SCHEMBL3870522 | 0.81 | MCHR1 (0.68) | MCHR1CHRM1HTR2ARAB9ANPC1 | |
| SCHEMBL26134296 | 0.81 | CHRM1 (0.67) | MCHR1CHRM1HTR2ACNR1RAB9A | |
| SCHEMBL4009683 | 0.81 | MCHR1 (1.00) | MCHR1CHRM1HTR2AKDM4EALDH1A1 | |
| SCHEMBL23747324 | 0.81 | CHRM1 (0.67) | MCHR1CHRM1HTR2ACNR1RAB9A | |
| SCHEMBL23747584 | 0.80 | CHRM1 (0.67) | MCHR1CHRM1HTR2ACNR1RAB9A | |
| SCHEMBL23747743 | 0.80 | CHRM1 (0.67) | MCHR1CHRM1HTR2ACNR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351719-B2 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-04-01 | — | — | US | disclosed |
| US-7351719-B2 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-04-01 | — | — | US | disclosed |
| US-7351719-B2 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-04-01 | — | — | US | disclosed |
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | MCHR2, MCHR1, NPY1R | MCHR1 2/4885CHRM1 124/4885HTR2A 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.