Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 10/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119278 | 0.92 | BDKRB1 (0.54) | BDKRB1BCHEACHEALDH1A1HTT | |
| SCHEMBL5117869 | 0.91 | BDKRB1 (0.50) | BDKRB1TP53ALDH1A1 | |
| SCHEMBL5118248 | 0.89 | BDKRB1 (0.43) | BDKRB1BCHEACHEALDH1A1HTT | |
| SCHEMBL5125633 | 0.89 | BDKRB1 (0.70) | BDKRB1ACLYTP53ALDH1A1HTT | |
| SCHEMBL5126485 | 0.87 | BDKRB1 (0.49) | BDKRB1BCHEACHETP53HTT | |
| SCHEMBL5124683 | 0.87 | BDKRB1 (0.49) | BDKRB1TP53 | |
| SCHEMBL5118568 | 0.87 | BDKRB1 (0.57) | BDKRB1TP53 | |
| SCHEMBL5114092 | 0.86 | BDKRB1 (0.43) | BDKRB1BCHEACHETP53ALDH1A1 | |
| SCHEMBL5118277 | 0.85 | BDKRB1 (0.66) | BDKRB1TP53 | |
| SCHEMBL5111773 | 0.85 | BDKRB1 (0.53) | BDKRB1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361687-B2 | Arylsulphonamide derivatives and methods of preparing | LABORATOIRES FOURNIER SA (FR) | 2008-04-22 | — | — | US | disclosed |
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | LABORATOIRES FOURNIER SA (FR) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | UGT1A1, UGT2B7, UGT1A6 | BDKRB1 1217/4885BCHE 3422/4885ACHE 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.