SCHEMBL5115040

SCHEMBL5115040

O=C(CCl)c1ccc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14436880 0.82 TSHR (0.84)
SCHEMBL10975814 0.80 TSHR (0.62)
SCHEMBL6536779 0.80
SCHEMBL18205594 0.80
SCHEMBL7464870 0.79 TSHR (0.61)
SCHEMBL10975817 0.79 TSHR (0.51)
SCHEMBL10676113 0.78
SCHEMBL6345873 0.78
SCHEMBL11572549 0.78
SCHEMBL12430457 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
JP-55015442-A None JP disclosed
JP-54110327-A None JP disclosed
US-20250388582-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF ILDONG PHARMACEUTICAL CO LTD (KR) 2025-12-25 US disclosed
EP-4556476-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF Ildong Pharmaceutical Co., Ltd. (KR) 2025-05-21 EP disclosed
WO-2024014885-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF 일동제약(주) 2024-01-18 WO disclosed
US-11028052-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2021-06-08 US disclosed
EP-3461816-B1 FIVE-MEMBERED HETEROCYLIC COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-03-24 EP disclosed
US-10421727-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2019-09-24 US disclosed
EP-3461816-A1 FIVE-MEMBERED HETEROCYLIC COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2019-04-03 EP disclosed
US-20040072693-A1 3-aminocarbonyl substituted benzoylpyrazolones BAYER INTELLECTUAL PROPERTY GMBH (DE) 2004-04-15 US disclosed
US-20030129081-A1 Thiazines and thiazoles as agents for protecting materials BAYER AKTIENGESELLSCHAFT (DE) 2003-07-10 US disclosed
WO-2003001913-A1 THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS BAYER CHEMICALS AG (DE) 2003-01-09 WO disclosed
EP-0084941-B1 AMIDE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-03-11 EP disclosed
US-4528282-A Amide derivatives IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1985-07-09 US disclosed
EP-0084941-A1 Amide derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-03 EP disclosed
JP-S5515442-A BACTERICIDAL FUNGICIDAL AGENT CONTAINING SUBSTITUTED PYRROLE NISSAN CHEM IND LTD 1980-02-02 JP disclosed
JP-S54110327-A FUNGICIDAL AND MILDEWCIDAL COMPOSITION CONTAINING PYRROLE DERIVATIVE NISSAN CHEM IND LTD 1979-08-29 JP disclosed
US-4068070-A ANGINA PECTORIS FUJI CHEMICAL INDUSTRY CO., LTD. (JA) 1978-01-10 US disclosed
US-3962247-A ANGINA PECTORIS FUJI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-06-08 US disclosed