Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632423 | 1.00 | PPM1B (0.53) | PPM1BPTPN1PPP1CCMEN1KMT2A | |
| SCHEMBL30546033 | 1.00 | PPM1B (0.53) | PPM1BPTPN1PPP1CCMEN1KMT2A | |
| SCHEMBL31162350 | 1.00 | PPM1B (0.53) | PPM1BPTPN1PPP1CCMEN1KMT2A | |
| SCHEMBL26040179 | 1.00 | PPM1B (0.53) | PPM1BPTPN1PPP1CCMEN1KMT2A | |
| SCHEMBL31162293 | 1.00 | PPM1B (0.53) | PPM1BPTPN1PPP1CCMEN1KMT2A | |
| SCHEMBL7104264 | 1.00 | PPM1B (0.53) | PPM1BPTPN1PPP1CCMEN1KMT2A | |
| SCHEMBL14996279 | 1.00 | PPM1B (0.53) | PPM1BPTPN1PPP1CCMEN1KMT2A | |
| SCHEMBL2318955 | 0.89 | PPM1B (0.56) | PPM1BPTPN1PPP1CCMEN1KMT2A | |
| SCHEMBL765159 | 0.89 | PPM1B (0.56) | PPM1BPTPN1PPP1CCMEN1KMT2A | |
| SCHEMBL3340559 | 0.89 | PPM1B (0.56) | PPM1BPTPN1PPP1CCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275241-A1 | Polymorphic Forms of Dolasetron Base and Processes of Preparing Dolasetron Base, Its Polymorphic Forms and Salt Thereof | USV LIMITED (IN) | 2008-11-06 | — | — | US | disclosed |
| US-20080275241-A1 | Polymorphic Forms of Dolasetron Base and Processes of Preparing Dolasetron Base, Its Polymorphic Forms and Salt Thereof | USV LIMITED (IN) | 2008-11-06 | — | — | US | disclosed |
| WO-2007072507-A2 | POLYMORPHIC FORMS OF DOLASETRON BASE AND PROCESSES OF PREPARING DOLASETRON BASE, ITS POLYMORPHIC FORMS AND SALT THEREOF | USV LIMITED (IN) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007072506-A2 | POLYMORPHIC FORMS OF DOLASETRON MESYLATE AND PROCESSES THEREOF | USV LIMITED (IN) | 2007-06-28 | — | — | WO | disclosed |
| EP-0994882-B1 | MANUFACTURE OF OPTICALLY ACTIVE HALOHYDRIN TRIALKYLSILYL ETHERS | DU PONT (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6207847-B1 | REACTING AN EPOXIDE WITH AN AZIDOTRIMETHYLSILANE; THEN HYDROCARBON HALIDE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275241-A1 | Polymorphic Forms of Dolasetron Base and Processes of Preparing Dolasetron Base, Its Polymorphic Forms and Salt Thereof | CYP4A11, CYP3A43, VKORC1 | PPM1B 3068/4885PTPN1 3690/4885PPP1CC 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.