Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.49 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958098 | 0.89 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL356526 | 0.89 | PIK3CD (0.62) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL357117 | 0.87 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL355226 | 0.86 | PIK3CD (0.65) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL355369 | 0.86 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL356148 | 0.86 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL355932 | 0.85 | PIK3CD (0.57) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL357152 | 0.85 | PIK3CD (0.57) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL357136 | 0.85 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL15686256 | 0.85 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275067-A1 | Quinazolinones as Inhibitors of Human Phosphatidylinositol 3-Kinase Delta | ICOS CORPORATION (US) | 2008-11-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275067-A1 | Quinazolinones as Inhibitors of Human Phosphatidylinositol 3-Kinase Delta | PIK3CD, PIK3CA, PI4KA | PIK3CD 1/4885PIK3CG 4/4885PIK3CB 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.