Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3521038 | 0.77 | HTT (0.58) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL3458498 | 0.77 | HTT (0.57) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL30665799 | 0.77 | HTT (0.57) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL516558 | 0.77 | HTT (0.57) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL27914649 | 0.76 | HTT (0.56) | HTTMAPTLMNAALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28203639 | 0.76 | HTT (0.56) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL27767382 | 0.74 | HTT (0.76) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL28517940 | 0.73 | HTT (0.55) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL11127797 | 0.73 | HTT (0.53) | HTTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL27605458 | 0.73 | HTT (0.55) | HTTMAPTLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785635-A1 | MMP-TARGETED THERAPEUTIC AND/OR DIAGNOSTIC NANOCARRIERS | Mallinckrodt LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013082389-A1 | MMP-TARGETED THERAPEUTIC AND/OR DIAGNOSTIC NANOCARRIERS | MALLINCKRODT INC. (US) | 2013-06-06 | — | — | WO | disclosed |
| EP-1687322-A4 | CUSTOM VECTORS FOR TREATING AND PREVENTING PANCREATIC CANCER | US GOV HEALTH & HUMAN SERV (US) | 2008-05-14 | — | — | EP | disclosed |
| EP-1687322-A2 | CUSTOM VECTORS FOR TREATING AND PREVENTING PANCREATIC CANCER | THERION BIOLOGICS CORPORATION (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005046622-A2 | CUSTOM VECTORS FOR TREATING AND PREVENTING PANCREATIC CANCER | THERION BIOLOGICS CORPORATION (US) | 2005-05-26 | — | — | WO | disclosed |