Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CFTR | P13569 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14098727 | 0.94 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4765190 | 0.86 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4721319 | 0.85 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14098892 | 0.85 | KIT (0.45) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5120018 | 0.85 | PTGER1 (0.55) | MAPTPTGER1RHEB | |
| Hydrochloric Acid SCHEMBL5117101 | 0.84 | KIT (0.44) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5130632 | 0.83 | KIT (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5125019 | 0.82 | KIT (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14098728 | 0.81 | CBFB (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14098729 | 0.81 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207708-A1 | Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders | GLAXO GROUP LIMITED (GB) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207708-A1 | Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders | PTGER1, PTGER2, PTGER4 | MEN1 3366/4885KMT2A 3173/4885ALDH1A1 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.