Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 6/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5125372 | 0.94 | BDKRB1 (0.44) | BDKRB1NR1H4HRH3POLBNPC1 | |
| SCHEMBL5114361 | 0.91 | BDKRB1 (0.50) | BDKRB1NR1H4BCHEACHENPC1 | |
| SCHEMBL5124589 | 0.87 | BDKRB1 (0.43) | BDKRB1NR1H4BCHEACHEPOLB | |
| SCHEMBL5125274 | 0.87 | BDKRB1 (0.52) | BDKRB1NR1H4NPC1RAB9A | |
| SCHEMBL5125872 | 0.85 | BDKRB1 (0.46) | BDKRB1HRH3POLBNPC1RAB9A | |
| SCHEMBL5118085 | 0.84 | NR1H4 (0.36) | BDKRB1NR1H4POLB | |
| SCHEMBL5126326 | 0.84 | BDKRB1 (0.52) | BDKRB1 | |
| SCHEMBL5126485 | 0.84 | BDKRB1 (0.49) | BDKRB1BCHEACHENPC1RAB9A | |
| SCHEMBL5111907 | 0.83 | BDKRB1 (0.45) | BDKRB1NR1H4POLB | |
| SCHEMBL5114367 | 0.82 | BDKRB1 (0.38) | BDKRB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361687-B2 | Arylsulphonamide derivatives and methods of preparing | LABORATOIRES FOURNIER SA (FR) | 2008-04-22 | — | — | US | disclosed |
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | LABORATOIRES FOURNIER SA (FR) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | UGT1A1, UGT2B7, UGT1A6 | BDKRB1 1217/4885NR1H4 15/4885HRH3 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.