SCHEMBL51207

SCHEMBL51207

CC(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
HSD17B1 P14061 1/20 0.67
LMNA P02545 2/20 0.62
HPGD P15428 4/20 0.59
ALDH1A1 P00352 4/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
CTDSP1 Q9GZU7 1/20 0.56
TAAR1 Q96RJ0 1/20 0.55
PTPN1 P18031 1/20 0.54
GSK3B P49841 1/20 0.54
PDCD1 Q15116 1/20 0.53
CD274 Q9NZQ7 1/20 0.53
KDM4E B2RXH2 1/20 0.53
USP2 O75604 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7738989 1.00 MAPT (1.00) MAPTSMN1; SMN2HSD17B1LMNAHPGD
SCHEMBL7252924 1.00 MAPT (1.00) MAPTSMN1; SMN2HSD17B1LMNAHPGD
Hydrogen Sulfide SCHEMBL28388826 0.98 MAPT (0.95) MAPTSMN1; SMN2HSD17B1LMNAHPGD
Water SCHEMBL9631565 0.98 MAPT (0.95) MAPTSMN1; SMN2HSD17B1LMNAHPGD
Formaldehyde SCHEMBL7590040 0.95 MAPT (0.91) MAPTSMN1; SMN2HSD17B1LMNAHPGD
Sulfur Dioxide SCHEMBL29197905 0.93 MAPT (0.87) MAPTSMN1; SMN2HSD17B1LMNAHPGD
SCHEMBL319943 0.93 MAPT (0.87) MAPTSMN1; SMN2HSD17B1LMNAHPGD
Biphenyl SCHEMBL1555184 0.92 MAPT (0.86) MAPTSMN1; SMN2HSD17B1LMNAHPGD
Acetophenone SCHEMBL27985201 0.92 MAPT (0.86) MAPTSMN1; SMN2HSD17B1LMNAHPGD
SCHEMBL8368648 0.91 MAPT (0.83) MAPTSMN1; SMN2HSD17B1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3084 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119156104-A Preparation method of photoelectric device, photoelectric device and display device 广东聚华新型显示研究院 2024-12-17 CN claimed
US-11952439-B2 Surface gradient cross-linking method of ultra-high molecular weight polyethylene and the application thereof b-ONE Medical (Suzhou) Co., Ltd. (CN) 2024-04-09 US claimed
CN-115925527-B Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2024-02-09 CN claimed
CN-117434165-A Method for detecting felbinac related substances 河北以岭医药研究院有限公司 2024-01-23 CN claimed
CN-117304135-A Synthesis method of 4-substituted-5H-1, 2, 3-dithiazole-5-thione and derivative 衡阳师范学院 2023-12-29 CN claimed
CN-117050110-A GPX4 and DHODH double-inhibition small molecule prodrug compound based on mitochondrial targeting and preparation method and application thereof 厦门大学 2023-11-14 CN claimed
CN-116640047-A Preparation method of 4-hydroxy biphenyl 上海筑裕新材料科技有限公司 2023-08-25 CN claimed
CN-113943218-B Preparation method and application of p-phenyl acetophenone 帕潘纳(北京)科技有限公司 2023-08-18 CN claimed
CN-116589715-A Surface gradient crosslinking method for ultra-high molecular weight polyethylene and application thereof 宽岳医疗器材(苏州)有限公司 2023-08-15 CN claimed
CN-112770789-B Surface gradient crosslinking method for ultra-high molecular weight polyethylene and application thereof 宽岳医疗器材(苏州)有限公司 2023-05-02 CN claimed
EP-0043480-B1 PROCESS FOR FORMING METALLIC IMAGES Hitachi, Ltd. (JP) 1985-04-03 EP claimed
US-4493904-A COORDINATION, POLYMERIZATION CATALYST CONTAINING TITANIUM TRICHORI CONOCO INC. (US) 1985-01-15 US claimed
US-4414275-A ETCHING, POLYVINYL FORMAL, PHOTOPOLYMERIZABLE ACRYLATE, RELEASE COATING LOCTITE (IRELAND) LIMITED (IE) 1983-11-08 US claimed
US-4347304-A PHOTOSENSITIZATION WITH DISILANES OR ORGANIC COMPOUNDS HAVING COUPLED GERMANIUM OR TIN MOLECULES; PHOTORESISTS; POSITIVES; PLATING HITACHI, LTD. (JP) 1982-08-31 US claimed
EP-0043480-A2 Process for forming metallic images Hitachi, Ltd. (JP) 1982-01-13 EP claimed
US-4125712-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1978-11-14 US claimed
US-4116692-A Photographic method utilizing a photosensitive composition containing a 2-azidobiphenyl and a triplet sensitizer AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1978-09-26 US claimed
US-4036818-A Method of preparing polymers of polyphenylene type KORSHAK VASILY VLADIMIROVICH 1977-07-19 US claimed
US-4020059-A Process for preparing tertiary amines NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JA) 1977-04-26 US claimed
US-3936447-A 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed