SCHEMBL5122473

SCHEMBL5122473

CCCN1C(=O)Cc2cc(N3C[C@H](CNC(=O)OC(C)(C)C)OC3=O)ccc21

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.46
MAOA P21397 4/20 0.46
LMNA P02545 1/20 0.46
PTGS1 P23219 1/20 0.46
CALML3 P27482 1/20 0.46
SDHA P31040 1/20 0.46
F10 P00742 12/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5122475 1.00 MAOB (0.46) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5510695 0.97 F10 (0.46) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5107723 0.94 MAOB (0.48) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5107726 0.94 MAOB (0.48) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5110336 0.92 MAOB (0.47) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5110332 0.92 MAOB (0.47) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5512875 0.91 MAOB (0.47) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5512879 0.91 MAOB (0.47) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5502701 0.90 F10 (0.47) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5120610 0.89 F10 (0.51) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents PFIZER INC 2008-10-23 US disclosed
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent JOSYULA VARA PRASAD V N 2006-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent OXA1L, MRPL21, RPS27L MAOB 1778/4885MAOA 1789/4885LMNA 4611/4885
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents OXA1L, OXSR1, OXER1 MAOB 412/4885MAOA 447/4885LMNA 4649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.