Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894747 | 0.94 | PPARG (0.51) | LMNAPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL4885359 | 0.94 | PPARA (0.52) | LMNATP53SMN1; SMN2PPARAPPARG | |
| SCHEMBL504044 | 0.94 | PPARG (0.54) | LMNATP53PPARAPPARGPPARD | |
| SCHEMBL4893815 | 0.91 | PPARA (0.50) | LMNAPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL3582601 | 0.90 | PPARA (0.53) | LMNAPOLBTP53PPARAPPARG | |
| SCHEMBL4889024 | 0.90 | PPARA (0.52) | LMNAPPARAPPARGPPARDMAPT | |
| SCHEMBL4893334 | 0.89 | TP53 (0.52) | LMNAPOLBTP53SMN1; SMN2PPARA | |
| SCHEMBL4894912 | 0.88 | POLB (0.54) | LMNAPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL4897132 | 0.88 | MAPT (0.46) | LMNAPOLBTP53SMN1; SMN2PPARA | |
| SCHEMBL5205220 | 0.88 | PPARG (0.43) | LMNAPOLBTP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080026067-A1 | Method for Increasing Specific Surface Area of Slightly Soluble Drug | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-31 | — | — | US | disclosed |
| EP-1741704-A1 | METHOD FOR INCREASING SPECIFIC SURFACE AREA OF SLIGHTLY SOLUBLE DRUG | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |