Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.38 |
| ▸ | CDK9 | P50750 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5126036 | 1.00 | GSR (0.40) | GSRLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5130420 | 1.00 | GSR (0.40) | GSRLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5972419 | 0.83 | EGFR (0.40) | GSRALDH1A1CCNT1CDK9CDK2 | |
| SCHEMBL5972411 | 0.83 | EGFR (0.40) | GSRALDH1A1CCNT1CDK9CDK2 | |
| SCHEMBL5123860 | 0.81 | MAPT (0.45) | LMNASMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL5123863 | 0.81 | MAPT (0.45) | LMNASMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL5120767 | 0.80 | MAPT (0.39) | HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5120760 | 0.80 | MAPT (0.39) | HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5126018 | 0.78 | MAPT (0.51) | SMN1; SMN2ALDH1A1CCNT1CDK9CDK2 | |
| SCHEMBL5126008 | 0.78 | MAPT (0.51) | SMN1; SMN2ALDH1A1CCNT1CDK9CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | NR5A1, ESRRA, AR | GSR 755/4885LMNA 2695/4885HPGD 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.