Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5124590 | 0.88 | TACR1 (0.64) | TACR1KCNH2 | |
| SCHEMBL5096115 | 0.85 | TACR1 (0.61) | TACR1KCNH2 | |
| SCHEMBL14176823 | 0.83 | TACR1 (0.66) | TACR1KCNH2 | |
| SCHEMBL14176822 | 0.82 | TACR1 (0.65) | TACR1KCNH2 | |
| SCHEMBL4317062 | 0.82 | TACR1 (0.74) | TACR1 | |
| Hydrochloric Acid SCHEMBL5123337 | 0.81 | TACR1 (0.62) | TACR1KCNH2 | |
| SCHEMBL5117210 | 0.81 | TACR1 (0.61) | TACR1KCNH2 | |
| Hydrochloric Acid SCHEMBL5129776 | 0.80 | TACR1 (0.60) | TACR1KCNH2 | |
| SCHEMBL5097047 | 0.79 | TACR1 (0.58) | TACR1KCNH2 | |
| SCHEMBL5091092 | 0.79 | TACR1 (0.58) | TACR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146588-A1 | Piperidinyl Piperidine Tachykinin Receptor Antagonists | MERCK SHARP & DOHME CORP. | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146588-A1 | Piperidinyl Piperidine Tachykinin Receptor Antagonists | TACR1, NPSR1, TACR2 | TACR1 1/4885KCNH2 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.