Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 13/20 | 0.72 |
| ▸ | HDAC4 | P56524 | 13/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.72 |
| ▸ | HDAC7 | Q8WUI4 | 13/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.72 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.72 |
| ▸ | HDAC11 | Q96DB2 | 13/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.72 |
| ▸ | HDAC9 | Q9UKV0 | 13/20 | 0.72 |
| ▸ | HDAC5 | Q9UQL6 | 13/20 | 0.72 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778838 | 0.86 | HDAC3 (0.77) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4774385 | 0.84 | HDAC3 (0.96) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4777866 | 0.84 | HDAC3 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydrochloric Acid SCHEMBL4779945 | 0.83 | HDAC3 (0.98) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Bromide SCHEMBL5131584 | 0.83 | HDAC3 (0.98) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4774373 | 0.82 | HDAC3 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14498713 | 0.81 | HDAC3 (0.98) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4795224 | 0.81 | HDAC3 (0.76) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4775537 | 0.79 | HDAC3 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Malic Acid SCHEMBL4777460 | 0.76 | HDAC3 (0.83) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073733-A1 | SALTS OF INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-06-19 | — | — | WO | claimed |