Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 5/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.32 |
| ▸ | TACR1 | P25103 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133091 | 0.92 | MDM2 (0.33) | MDM2CDK2CSNK1A1CSNK1DCDK7 | |
| SCHEMBL5049263 | 0.91 | TACR1 (0.35) | MDM2CDK2CSNK1A1CSNK1DCDK7 | |
| SCHEMBL5624618 | 0.91 | CDK2 (0.34) | MDM2CDK2CSNK1A1CSNK1DCDK7 | |
| SCHEMBL5132449 | 0.88 | BRAF (0.37) | BRAFPIK3CDTACR1 | |
| SCHEMBL5042833 | 0.87 | CETP (0.39) | MDM2CDK2CSNK1A1CSNK1DCDK7 | |
| SCHEMBL5042944 | 0.87 | CETP (0.33) | MDM2CDK2CSNK1A1CSNK1DCDK7 | |
| SCHEMBL5046633 | 0.85 | CETP (0.39) | MDM2CDK2CSNK1A1CSNK1DCDK7 | |
| SCHEMBL18259014 | 0.84 | MDM2 (0.33) | MDM2CDK2CSNK1A1CSNK1DCDK7 | |
| SCHEMBL5050202 | 0.83 | CETP (0.34) | MDM2CDK2CSNK1A1CSNK1DCDK7 | |
| SCHEMBL5042738 | 0.82 | CETP (0.45) | BRAFPIK3CDTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981342-B1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDYS LAB LTD DR (IN) | 2016-11-30 | — | — | EP | disclosed |
| EP-1981342-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007075194-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | disclosed |