SCHEMBL5133103

SCHEMBL5133103

CC(C)N1CCC(Oc2ccc3cc(OC(=O)N(C)Cc4ccccc4)ccc3c2)CC1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4507448 0.87 HRH3 (0.59) HRH3
SCHEMBL4500820 0.82 HRH3 (0.59) HRH3
SCHEMBL4487256 0.80 HRH3 (0.57) HRH3
SCHEMBL4499090 0.80 HRH3 (0.57) HRH3
SCHEMBL5133616 0.76 HRH3 (0.53) HRH3
SCHEMBL4507419 0.76 HRH3 (0.60) HRH3
SCHEMBL2211797 0.76 HRH3 (0.58) HRH3
SCHEMBL4485809 0.75 HRH3 (0.65) HRH3
SCHEMBL5023005 0.75 HRH3 (0.59) HRH3
SCHEMBL4501705 0.75 HRH3 (0.74) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1755593-B1 NAPHTHALENE DERIVATIVES USEFUL AS HISTAMINE-3-RECEPTOR LIGANDS HOFFMANN LA ROCHE (CH) 2008-01-16 EP claimed