Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675799 | 0.87 | PDE4D (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3667700 | 0.87 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3549578 | 0.87 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3673863 | 0.87 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3547514 | 0.86 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3679312 | 0.86 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3672014 | 0.85 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3674617 | 0.85 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3667766 | 0.84 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3677039 | 0.84 | PDE4B (0.58) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948167-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-07-30 | — | — | EP | claimed |
| WO-2007045980-A1 | COMPOSITIONS OF PHOSPHODIESTERASE TYPE IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | claimed |