Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 19/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876337 | 0.90 | P2RY12 (0.77) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL3217388 | 0.86 | P2RY12 (0.82) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4874256 | 0.83 | P2RY12 (0.77) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4874293 | 0.81 | P2RY12 (0.78) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL5057909 | 0.79 | P2RY12 (0.63) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL3226299 | 0.79 | P2RY12 (0.80) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4876674 | 0.78 | P2RY12 (0.76) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL4739704 | 0.77 | P2RY12 (0.84) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL3224743 | 0.77 | P2RY12 (0.83) | P2RY12CYP2C9CYP3A4CHRM2DRD3 | |
| SCHEMBL3223721 | 0.77 | P2RY12 (1.00) | P2RY12CYP2C9CYP3A4CHRM2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904474-A1 | NEW PYRIDINE ANALOGUES | AstraZeneca AB (SE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007008140-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |