SCHEMBL5133687

SCHEMBL5133687

NCCCCC([C]=O)N(N)N

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.35
RNPEP Q9H4A4 1/20 0.34
NFKB1 P19838 1/20 0.32
CPB2 Q96IY4 2/20 0.31
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA3 P07451 2/20 0.30
CA4 P22748 2/20 0.30
CA6 P23280 2/20 0.30
CA5A P35218 2/20 0.30
CA7 P43166 2/20 0.30
CA9 Q16790 2/20 0.30
CA14 Q9ULX7 2/20 0.30
CA5B Q9Y2D0 2/20 0.30
DNM1 Q05193 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5133688 1.00 GSR (0.35) GSRRNPEPNFKB1CPB2CA12
SCHEMBL15529854 0.80 CHRM2 (0.34) GSRRNPEPNFKB1CPB2
SCHEMBL3952652 0.74 GSR (0.38) GSRRNPEPNFKB1CPB2
SCHEMBL42855 0.69
SCHEMBL42856 0.69
SCHEMBL27722441 0.67 GSR (0.43) GSRRNPEPNFKB1CPB2CA12
SCHEMBL42857 0.67
SCHEMBL28972436 0.64 GSR (0.40) GSRRNPEPNFKB1CPB2CA12
SCHEMBL10784463 0.64 GSR (0.35) GSRRNPEPNFKB1CPB2CA12
SCHEMBL9836643 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7319000-B1 Compositions and methods for eliciting immune or anti-infective responses BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-01-15 US disclosed
US-20020151678-A1 Prophylaxis and therapy of acquired immunodeficiency syndrome BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM. 2002-10-17 US disclosed
US-6265539-B1 PEPTIDE FOR USE IN VACCINATION AND PREVENTION OF VIRAL INFECTION; FOR KILLING CELLS EXPRESSING PREFERENTIAL VIRAL PROTEIN THE UNIVERSITY OF TEXAS SYSTEM THE BOARD OF REGENTS 2001-07-24 US disclosed
US-6210873-B1 SCREENING BY INTRADERMALLY IMMUNIZING ANIMAL WITH SYNTHETIC PEPTIDE, RECOVERING CELLS FROM LYMPH NODES CLOSE TO SITE, DETERMINING WHETHER CELLS CAN LYSE MAJOR HISTOCOMPATIBILITY COMPLEX-MATCHED TARGET CELLS HAVING PEPTIDE ON SURFACE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2001-04-03 US disclosed
EP-0671947-B1 COMPOSITIONS FOR ELICITING CYTOTOXIC T-LYMPHOCYTE RESPONSES AGAINST VIRUSES UNIV TEXAS (US) 2000-03-08 EP disclosed
EP-0968721-A2 Use of a composition comprising a peptide for the inhibition of HIV THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2000-01-05 EP disclosed
EP-0671947-A1 COMPOSITIONS FOR ELICITING CYTOTOXIC T-LYMPHOCYTE RESPONSES AGAINST VIRUSES THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-09-20 EP disclosed
WO-1993010816-A1 COMPOSITIONS FOR ELICITING CYTOTOXIC T-LYMPHOCYTE RESPONSES AGAINST VIRUSES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-06-10 WO disclosed
EP-0491861-A4 PROPHYLAXIS AND THERAPY OF ACQUIRED IMMUNODEFICIENCY SYNDROME 1992-10-07 EP disclosed
US-5128319-A Prophylaxis and therapy of acquired immunodeficiency syndrome BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-07-07 US disclosed
EP-0491861-A1 PROPHYLAXIS AND THERAPY OF ACQUIRED IMMUNODEFICIENCY SYNDROME BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-07-01 EP disclosed
WO-1991004045-A1 PROPHYLAXIS AND THERAPY OF ACQUIRED IMMUNODEFICIENCY SYNDROME BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1991-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151678-A1 Prophylaxis and therapy of acquired immunodeficiency syndrome SERPINA6, CD4, VSIG8 GSR 3803/4885RNPEP 159/4885NFKB1 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.