Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706495 | 0.84 | TMEM97 (0.41) | TMEM97KMOKCNH2 | |
| SCHEMBL923788 | 0.79 | CNR2 (0.43) | KMOKCNH2 | |
| SCHEMBL707920 | 0.77 | TACR1 (0.38) | TMEM97KMOKCNH2 | |
| SCHEMBL27773476 | 0.76 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL921242 | 0.72 | KCNH2 (0.64) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4298769 | 0.66 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL11711208 | 0.66 | TMEM97 (0.42) | TMEM97 | |
| SCHEMBL4776915 | 0.66 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL4777392 | 0.62 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL707012 | 0.61 | TMEM97 (0.38) | TMEM97KCNH2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893599-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | AstraZeneca AB (SE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006134378-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2006-12-21 | — | — | WO | disclosed |