Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 4/20 | 0.64 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.64 |
| ▸ | CDK2 | P24941 | 2/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.64 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.58 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 9/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 6/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3523508 | 0.81 | CSNK1E (0.80) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3520464 | 0.78 | CDK2 (0.67) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3520179 | 0.77 | CSNK1E (0.80) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL27721073 | 0.76 | CSNK1E (0.76) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL12023960 | 0.75 | CSNK1E (0.60) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL1728799 | 0.75 | CSNK1E (0.65) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3528432 | 0.74 | CSNK1E (0.59) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL1730283 | 0.74 | CSNK1E (0.64) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3526247 | 0.73 | CSNK1E (0.71) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL6217129 | 0.73 | MAPK14 (1.00) | CSNK1ECCNA2CDK2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928237-A2 | NOVEL IMIDAZO BASED HETEROCYCLES | Abbott Laboratories (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028051-A2 | NOVEL IMIDAZO BASED HETEROCYCLES | ABBOTT LABORATORIES (US) | 2007-03-08 | — | — | WO | disclosed |