Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.36 |
| ▸ | CETP | P11597 | 14/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046870 | 0.86 | TACR1 (0.38) | TACR1CETPKCNH2 | |
| SCHEMBL5134237 | 0.84 | CETP (0.35) | TACR1CETP | |
| SCHEMBL5042938 | 0.78 | CETP (0.37) | CETP | |
| SCHEMBL5043271 | 0.72 | TACR1 (0.44) | TACR1 | |
| SCHEMBL5050175 | 0.71 | TACR1 (0.37) | TACR1CETP | |
| SCHEMBL14602979 | 0.71 | TACR1 (0.38) | TACR1CETPKCNH2 | |
| SCHEMBL5046871 | 0.69 | CETP (0.38) | TACR1CETP | |
| SCHEMBL17414291 | 0.69 | CETP (0.37) | TACR1CETPKCNH2 | |
| SCHEMBL15739415 | 0.65 | CETP (0.35) | TACR1CETP | |
| SCHEMBL14602976 | 0.65 | CETP (0.38) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981342-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007075194-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | claimed |