⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880919 | 0.64 | — | — | |
| SCHEMBL12983713 | 0.58 | — | — | |
| SCHEMBL2175146 | 0.53 | — | — | |
| SCHEMBL3542283 | 0.53 | — | — | |
| SCHEMBL1866401 | 0.53 | — | — | |
| Hydrochloric Acid SCHEMBL29260638 | 0.51 | — | — | |
| SCHEMBL444308 | 0.46 | — | — | |
| SCHEMBL13057793 | 0.43 | — | — | |
| SCHEMBL21500439 | 0.43 | — | — | |
| SCHEMBL23234265 | 0.38 | MEN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE44354-E1 | Amyloid plaque aggregation inhibitors and diagnostic imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-07-09 | — | — | US | disclosed |
| US-7425318-B2 | Amyloid plaque aggregation inhibitors and diagnostic imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-09-16 | — | — | US | disclosed |
| EP-1381604-B1 | AMYLOID PLAQUE AGGREGATION INHIBITORS AND DIAGNOSTIC IMAGING AGENTS | UNIV PENNSYLVANIA (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20060051293-A1 | Amyloid plaque aggregation inhibitors and diagnostic imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-03-09 | — | — | US | disclosed |
| US-6946116-B2 | Amyloid plaque aggregation inhibitors and diagnostic imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2005-09-20 | — | — | US | disclosed |
| US-20040131545-A1 | Amyloid plaque aggregation inhibitors and diagnostic imaging agents | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2004-07-08 | — | — | US | disclosed |
| US-6696039-B2 | 2-PHENYL-IMIDAZO(1,2A)PYRIDINE DERIVATIVES | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2004-02-24 | — | — | US | disclosed |
| EP-1381604-A2 | AMYLOID PLAQUE AGGREGATION INHIBITORS AND DIAGNOSTIC IMAGING AGENTS | University of Pennsylvania - Centre for Technology (US) | 2004-01-21 | — | — | EP | disclosed |
| US-20030059369-A1 | Amyloid plaque aggregation inhibitors and diagnostic imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2003-03-27 | — | — | US | disclosed |
| WO-2002085903-A2 | AMYLOID PLAQUE AGGREGATION INHIBITORS AND DIAGNOSTIC IMAGING AGENTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2002-10-31 | — | — | WO | disclosed |