⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584416 | 0.73 | TSHR (0.38) | — | |
| SCHEMBL10699564 | 0.73 | CYP3A4 (0.44) | — | |
| SCHEMBL5586542 | 0.71 | PTPN1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7212773 | 0.71 | BLM (0.40) | — | |
| SCHEMBL9806461 | 0.68 | TSHR (0.34) | — | |
| SCHEMBL1493619 | 0.66 | TSHR (0.53) | — | |
| SCHEMBL1489814 | 0.63 | — | — | |
| SCHEMBL11869445 | 0.62 | — | — | |
| SCHEMBL156789 | 0.61 | TSHR (0.34) | — | |
| SCHEMBL15877804 | 0.60 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080152640-A1 | Means and Methods For Treating a Disease Which is Associated With an Excess Transport of Hyaluronan Across a Lipid Bilayer | UNIVERSITATSKLINIKUM MUNSTER (DE) | 2008-06-26 | — | — | US | disclosed |
| EP-1660072-A2 | MEANS AND METHODS FOR TREATING A DISEASE WHICH IS ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN ACROSS A LIPID BILAYER | Universitätsklinikum Münster (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005013947-A2 | MEANS AND METHODS FOR TREATING A DISEASE WHICH IS ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN ACROSS A LIPID BILAYER | Universitätsklinikum Münster (DE) | 2005-02-17 | — | — | WO | disclosed |