SCHEMBL51347

SCHEMBL51347

Cc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.76
RAPGEF4 Q8WZA2 2/20 0.62
ACHE P22303 1/20 0.62
PKM P14618 2/20 0.61
ENPP2 Q13822 1/20 0.56
MAPT P10636 2/20 0.55
MEN1 O00255 1/20 0.55
ALDH1A1 P00352 1/20 0.55
KMT2A Q03164 1/20 0.55
LMNA P02545 2/20 0.52
HTT P42858 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ELANE P08246 1/20 0.52
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10035480 1.00 GAA (0.76) GAARAPGEF4ACHEPKMENPP2
SCHEMBL12301432 0.94 GAA (0.67) GAARAPGEF4ACHEPKMENPP2
SCHEMBL8597474 0.94 GAA (0.67) GAARAPGEF4ACHEPKMENPP2
SCHEMBL15681791 0.88 HTT (0.71) GAARAPGEF4ACHEPKMMAPT
SCHEMBL21934883 0.88 HTT (0.71) GAARAPGEF4ACHEPKMMAPT
SCHEMBL15926451 0.88 HTT (0.71) GAARAPGEF4ACHEPKMMAPT
SCHEMBL15681793 0.88 GAA (0.59) GAARAPGEF4ACHEPKMENPP2
SCHEMBL12300188 0.88 HTT (0.71) GAARAPGEF4ACHEPKMMAPT
SCHEMBL16771243 0.88 HTT (0.71) GAARAPGEF4ACHEPKMMAPT
SCHEMBL17277953 0.88 HTT (0.71) GAARAPGEF4ACHEPKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 843 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026934-A N-azole-4-methylbenzenesulfonamide compound and preparation method and application thereof 安徽理工大学 2024-05-14 CN claimed
EP-1976829-A2 N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS GENELABS TECHNOLOGIES, INC. (US) 2008-10-08 EP claimed
US-20070265262-A1 N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS GENELABS TECHNOLOGIES, INC. 2007-11-15 US claimed
WO-2007070556-A2 N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS GENELABS TECHNOLOGIES, INC. (US) 2007-06-21 WO claimed
EP-1060904-B1 A thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP claimed
US-6583086-B1 Good image preservability of recorded part, good resistance to humid and heat resistance NIPPON PAPER INDUSTRIES CO. LTD. (JP) 2003-06-24 US claimed
WO-2000026037-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-11 WO claimed
US-5238768-A Toner compositions with sulfone charge enhancing additives XEROX CORPORATION (US) 1993-08-24 US claimed
EP-0181646-B1 HEAT-SENSITIVE REGISTRATION FOIL JUJO PAPER CO., LTD. (JP) 1989-10-11 EP claimed
EP-0112291-B1 HEAT-SENSITIVE REGISTRATION MATERIAL CIBA-GEIGY AG (CH) 1987-01-28 EP claimed
US-4630080-A CONTAINING CALCIUM MONOBENZY PHTHALATE AS STABILIZER, AND A DIPHENYLSULFONE AS DEVELOPER FOR COLORLESS DYE JUJO PAPER CO., LTD. (JP) 1986-12-16 US claimed
US-4611072-A Heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1986-09-09 US claimed
EP-0181646-A2 Heat-sensitive registration foil JUJO PAPER CO., LTD. (JP) 1986-05-21 EP claimed
US-4590498-A HEAT AND PRESSURE SENESITIVE ELEMENTS; HIGH SPEED; FLORAN DYES; INTENSITY SHIN NISSO KAKO CO., LTD. (JP) 1986-05-20 US claimed
US-4536779-A PHENOLSULFONYL SALT AS DEVELOPER FOR COLOR FORMER CIBA-GEIGY CORPORATION (US) 1985-08-20 US claimed
US-4502066-A STABILIZERS OF P-ALKYL- OR O-BENZOYLBENZOIC ACID METAL SALTS; OIL REPELLANTS JUJO PAPER CO., LTD. (JP) 1985-02-26 US claimed
EP-0112291-A2 Heat-sensitive registration material CIBA-GEIGY AG (CH) 1984-06-27 EP claimed
JP-61146593-A None JP disclosed
EP-0083204-A2 2-Aminophenol derivatives and process for their preparation ONO PHARMACEUTICAL CO., LTD. (JP) 1983-07-06 EP disclosed
EP-0067793-A2 Pressure or heat sensitive recording materials CIBA-GEIGY AG (CH) 1982-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265262-A1 N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS ZC3HAV1, HAVCR2, ZC3HAV1L GAA 940/4885RAPGEF4 4319/4885ACHE 2616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.