Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.61 |
| ▸ | HMGCR | P04035 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071774 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL11175213 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL290566 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL513302 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL9374800 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL11066113 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL23040316 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL9211891 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL1523678 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL | |
| SCHEMBL10796010 | 1.00 | PTPN7 (0.61) | PTPN7HMGCRTSHRTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106620682-A | Liposomal vaccine preparation and use thereof, as well as method for producing IgG antibody | 华中师范大学 | 2017-05-10 | — | — | CN | disclosed |
| US-8758777-B2 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2014-06-24 | — | — | US | disclosed |
| US-20120027809-A1 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2012-02-02 | — | — | US | disclosed |
| CN-102112214-A | Functionalized thin film polyamide membranes | POLYMERS CRC LTD | 2011-06-29 | — | — | CN | disclosed |